CellGro® hUC MSC

Human Umbilical Cord-Derived Multipotent Mesenchymal Stromal Cells

Mesenchymal stem/stromal cells (MSC) are self-renewing cells that hold great therapeutic promise in the field of cell-based tissue engineering and regenerative medicine. They are used for the prevention or treatment of Graft versus Host Disease (GvHD) and co culture of cord blood cells with MSC results in improved expansion of hematopoietic progenitors.(1,2,3)

CellGro® hUC-MSC are isolated from umbilical cord tissue by enzymatic digestion after removal of vessels. The cells are assayed for their capacity to expand, their immuno phenotype, and for their potential to differentiate in vitro into adipogenic, osteogenic and chondrogenic lineages.

Characteristics

CellGro® hUC-MSC have been cultured serum-free before freezing using CellGro® MSC Medium containing 5 ng/ml CellGro® FGF-2



Related products

CellGro® MSC Medium
Serum-free medium developed for the optimal expansion of MSCs from umbilical cord matrix and blood

CellGro® Gelatin
Sterile, 0.1 % (w/v) ready to use solution in 0.9 % (w/v) sodium chloride

CellGro® FGF-2
Human recombinant FGF-2 lyophilized from a sterile-filtered solution without carrier protein

Quality controls include

  • bacteria and fungi
  • mycoplasma
  • HIV-1 / HBV / HCV (analyzed using maternal blood)

Intended Use

  • for preclinical ex vivo use
  • not intended for therapeutic use

Documentation

  • certificate of analysis
  • product data sheet (download data sheet)
  • detailed handling instruction (on request)
 
  1. Ringden O et al. Mesenchymal stem cells for treatment of acute and chronic graft-versus-host disease, tissue toxicity and hemophages. Best Practice & Research Clinical Hematology 2011; 24: 65-72
  2. McGuirk JP and Weiss ML. Promising cellular therapeutics for prevention or management of graft-versus-host disease. Placenta 2011: 32: S303-S310
  3. Robinson SN et al. Mesenchymal stem cells in ex vivo cord blood expression. Best Practice & Research Clinical Hematology 2011: 24: 83-91