Mesenchymal Stem Cells
Mesenchymal Stem Cells (MSCs), also called Mesenchymal Stromal Cells, are multipotent stem cells that can be differentiated into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, beta-panreatic islets cells and potentially neuronal cells. The cells can be isolated for diverse tissues including bone marrow, adipose tissue, umbilical cord, bone and muscle. MSCs hold great therapeutic promise in the field of cell-based tissue engineering and regenerative medicine. They are also being used for the prevention or treatment of GvHD after allogeneic blood stem cell transplantation to improve engraftment of HSC in vivo and expansion of HSCs in vitro.
Their immunomodulatory properties are furthermore employed in autoimmune diseases such as diabetes.